Researchers from UC Santa Cruz, UC Davis, LuxiTech, and Soochow University have developed a new method to run AI language models more efficiently by eliminating matrix multiplication, potentially reducing the environmental impact and operational costs of AI systems. Ars Technica's Benj Edwards reports: Matrix multiplication (often abbreviated to "MatMul") is at the center of most neural network computational tasks today, and GPUs are particularly good at executing the math quickly because they can perform large numbers of multiplication operations in parallel. [...] In the new paper, titled "Scalable MatMul-free Language Modeling," the researchers describe creating a custom 2.7 billion parameter model without using MatMul that features similar performance to conventional large language models (LLMs). They also demonstrate running a 1.3 billion parameter model at 23.8 tokens per second on a GPU that was accelerated by a custom-programmed FPGA chip that uses about 13 watts of power (not counting the GPU's power draw). The implication is that a more efficient FPGA "paves the way for the development of more efficient and hardware-friendly architectures," they write.

The paper doesn't provide power estimates for conventional LLMs, but this post from UC Santa Cruz estimates about 700 watts for a conventional model. However, in our experience, you can run a 2.7B parameter version of Llama 2 competently on a home PC with an RTX 3060 (that uses about 200 watts peak) powered by a 500-watt power supply. So, if you could theoretically completely run an LLM in only 13 watts on an FPGA (without a GPU), that would be a 38-fold decrease in power usage. The technique has not yet been peer-reviewed, but the researchers -- Rui-Jie Zhu, Yu Zhang, Ethan Sifferman, Tyler Sheaves, Yiqiao Wang, Dustin Richmond, Peng Zhou, and Jason Eshraghian -- claim that their work challenges the prevailing paradigm that matrix multiplication operations are indispensable for building high-performing language models. They argue that their approach could make large language models more accessible, efficient, and sustainable, particularly for deployment on resource-constrained hardware like smartphones. [...]

The researchers say that scaling laws observed in their experiments suggest that the MatMul-free LM may also outperform traditional LLMs at very large scales. The researchers project that their approach could theoretically intersect with and surpass the performance of standard LLMs at scales around 10^23 FLOPS, which is roughly equivalent to the training compute required for models like Meta's Llama-3 8B or Llama-2 70B. However, the authors note that their work has limitations. The MatMul-free LM has not been tested on extremely large-scale models (e.g., 100 billion-plus parameters) due to computational constraints. They call for institutions with larger resources to invest in scaling up and further developing this lightweight approach to language modeling.

China brought a capsule full of lunar soil [non-paywalled link] from the far side of the moon down to Earth on Tuesday, achieving the latest success in an ambitious schedule to explore the moon and other parts of the solar system. From a report: The sample, retrieved by the China National Space Administration's Chang'e-6 lander after a 53-day mission, highlights China's growing capabilities in space and notches another win in a series of lunar missions that started in 2007 and have so far been executed almost without flaw. "Chang'e-6 is the first mission in human history to return samples from the far side of the moon," Long Xiao, a planetary geologist at China University of Geosciences, wrote in an email. "This is a major event for scientists worldwide," he added, and "a cause for celebration for all humanity."

Such sentiments and the prospects of international lunar sample exchanges highlighted the hope that China's robotic missions to the moon and Mars will serve to advance scientific understanding of the solar system. Those possibilities are contrasted by views in Washington and elsewhere that Tuesday's achievement is the latest milestone in a 21st-century space race with geopolitical overtones. In February, a privately operated American spacecraft landed on the moon. NASA is also pursuing the Artemis campaign to return Americans to the lunar surface, although its next mission, a flight by astronauts around the moon, has been delayed because of technical issues. China, too, is looking to expand its presence on the moon, landing more robots there, and eventually human astronauts, in the years to come.

India is set to embark on an ambitious $168 billion project to link its major rivers, aiming to address water scarcity and boost agriculture in the world's most populous nation. The National River Linking Project, conceived over a century ago, plans to construct 30 canals to transfer an estimated 7 trillion cubic feet of water annually across the country. While government officials tout the project's potential to irrigate farmland and generate hydroelectric power, scientists and environmental experts have raised concerns about its ecological impact. Recent research suggests the project could disrupt monsoon patterns, potentially exacerbating water stress in some regions.

Passant Rabie reports via Gizmodo: A video circulating online appears to show debris from a Chinese rocket falling above a populated area, with residents running for cover as a heavy cloud of dark yellow smoke trails across the sky in a frightening scene. The suspected debris may have come from China's Long March 2C rocket, which launched on Saturday, June 22, carrying a joint mission by China and France to study Gamma-ray bursts. The launch was declared a success, but its aftermath was captured by videos posted to Chinese social media sites.

The videos show what appears to be the first stage rocket booster of the Long March 2C rocket tumbling uncontrollably over a village in southwest China, while local residents cover their ears and run for shelter from the falling debris. There are no reports of injuries or damage to property. That said, unverified video and images show a gigantic cloud erupting at the site of the crashed rocket, and the booster itself seemingly next to a roadway. The first stage of the rocket can be seen leaking fuel, the color of which is consistent with nitrogen tetroxide. The chemical compound is a strong oxidizing agent that is used for rocket propulsion but it can be fatally toxic, according to Jonathan McDowell, astrophysicist at the Harvard-Smithsonian Center.

"It's known in the rocket industry as BFRC, a big fucking red cloud," McDowell told Gizmodo. "And when you see a BFRC, you run for your life." Nitrogen tetroxide was accepted as the rocket propellant oxidizer of choice in the early 1950s by the U.S.S.R. and the United States, however it became less commonly used over the years because it is extremely toxic, according to NASA (PDF). If it comes in contact with skin, eyes, or respiratory system, it can destroy human tissue, and if inhaled through the lungs, it can lead to a build up of fluids or, in extreme cases, death. "It's pretty scary, but this is just how the Chinese do business," McDowell told Gizmodo. "They have a different level of acceptable public risk." "I think over a 10 year period, we may see the older rockets phased out but they're not in any hurry to do so," added McDowell. "They're still launching one a week or something like that, and they are really quite dangerous."

It's been a 1,000 years since there was a significant volcanic eruption from Mount Rainier, CNN reminds readers. It's a full 60 miles from Tacoma, Washington — and 90 miles from Seattle. Yet "more than Hawaii's bubbling lava fields or Yellowstone's sprawling supervolcano, it's Mount Rainier that has many U.S. volcanologists worried."

"Mount Rainier keeps me up at night because it poses such a great threat to the surrounding communities, said Jess Phoenix, a volcanologist and ambassador for the Union of Concerned Scientists, on an episode of CNN's series "Violent Earth With Liv Schreiber." The sleeping giant's destructive potential lies not with fiery flows of lava, which, in the event of an eruption, would be unlikely to extend more than a few miles beyond the boundary of Mount Rainier National Park in the Pacific Northwest. And the majority of volcanic ash would likely dissipate downwind to the east away from population centers, according to the US Geological Survey. Instead, many scientists fear the prospect of a lahar — a swiftly moving slurry of water and volcanic rock originating from ice or snow rapidly melted by an eruption that picks up debris as it flows through valleys and drainage channels.

"The thing that makes Mount Rainier tough is that it is so tall, and it's covered with ice and snow, and so if there is any kind of eruptive activity, hot stuff ... will melt the cold stuff and a lot of water will start coming down," said Seth Moran, a research seismologist at USGS Cascades Volcano Observatory in Vancouver, Washington. "And there are tens, if not hundreds of thousands of people who live in areas that potentially could be impacted by a large lahar, and it could happen quite quickly." The deadliest lahar in recent memory was in November 1985 when Colombia's Nevado del Ruiz volcano erupted. Just a couple hours after the eruption started, a river of mud, rocks, lava and icy water swept over the town of Armero, killing over 23,000 people in a matter of minutes... Bradley Pitcher, a volcanologist and lecturer in Earth and environmental sciences at Columbia University, said in an episode of CNN's "Violent Earth"... said that Mount Rainier has about eight times the amount of glaciers and snow as Nevado del Ruiz had when it erupted. "There's the potential to have a much more catastrophic mudflow...."

Lahars typically occur during volcanic eruptions but also can be caused by landslides and earthquakes. Geologists have found evidence that at least 11 large lahars from Mount Rainier have reached into the surrounding area, known as the Puget Lowlands, in the past 6,000 years, Moran said.
Two major U.S. cities — Tacoma and South Seattle — "are built on 100-foot-thick (30.5-meter) ancient mudflows from eruptions of Mount Rainier," the volcanologist said on CNN's "Violent Earth" series.

CNN's article adds that the US Geological Survey already set up a lahar detection system at Mount Rainier in 1998, "which since 2017 has been upgraded and expanded. About 20 sites on the volcano's slopes and the two paths identified as most at risk of a lahar now feature broadband seismometers that transmit real-time data and other sensors including trip wires, infrasound sensors, web cameras and GPS receivers."

Tuesday a SpaceX Falcon Heavy rocket will launch a special satellite — a state-of-the-art weather-watcher from America's National Oceanic and Atmospheric Administration.

It will complete a series of four GOES-R satellite launches that began in 2016. Space.com drills down into how these satellites have changed weather forecasts: More than seven years later, with three of the four satellites in the series orbiting the Earth, scientists and researchers say they are pleased with the results and how the advanced technology has been a game changer. "I think it has really lived up to its hype in thunderstorm forecasting. Meteorologists can see the convection evolve in near real-time and this gives them enhanced insight on storm development and severity, making for better warnings," John Cintineo, a researcher from NOAA's National Severe Storms Laboratory , told Space.com in an email.

"Not only does the GOES-R series provide observations where radar coverage is lacking, but it often provides a robust signal before radar, such as when a storm is strengthening or weakening. I'm sure there have been many other improvements in forecasts and environmental monitoring over the last decade, but this is where I have most clearly seen improvement," Cintineo said. In addition to helping predict severe thunderstorms, each satellite has collected images and data on heavy rain events that could trigger flooding, detected low clouds and fog as it forms, and has made significant improvements to forecasts and services used during hurricane season. "GOES provides our hurricane forecasters with faster, more accurate and detailed data that is critical for estimating a storm's intensity, including cloud top cooling, convective structures, specific features of a hurricane's eye, upper-level wind speeds, and lightning activity," Ken Graham, director of NOAA's National Weather Service told Space.com in an email.

Instruments such as the Advanced Baseline Imager have three times more spectral channels, four times the image quality, and five times the imaging speed as the previous GOES satellites. The Geostationary Lightning Mapper is the first of its kind in orbit on the GOES-R series that allows scientists to view lightning 24/7 and strikes that make contact with the ground and from cloud to cloud. "GOES-U and the GOES-R series of satellites provides scientists and forecasters weather surveillance of the entire western hemisphere, at unprecedented spatial and temporal scales," Cintineo said. "Data from these satellites are helping researchers develop new tools and methods to address problems such as lightning prediction, sea-spray identification (sea-spray is dangerous for mariners), severe weather warnings, and accurate cloud motion estimation. The instruments from GOES-R also help improve forecasts from global and regional numerical weather models, through improved data assimilation."
The final satellite, launching Tuesday, includes a new sensor — the Compact Coronagraph — "that will monitor weather outside of Earth's atmosphere, keeping an eye on what space weather events are happening that could impact our planet," according to the article.

"It will be the first near real time operational coronagraph that we have access to," Rob Steenburgh, a space scientist at NOAA's Space Weather Prediction Center, told Space.com on the phone. "That's a huge leap for us because up until now, we've always depended on a research coronagraph instrument on a spacecraft that was launched quite a long time ago."

"A Chinese launch of the joint Sino-French SVOM mission to study Gamma-ray bursts early Saturday saw toxic rocket debris fall over a populated area..." writes Space News: SVOM is a collaboration between the China National Space Administration (CNSA) and France's Centre national d'études spatiales (CNES). The mission will look for high-energy electromagnetic radiation from these events in the X-ray and gamma-ray ranges using two French and two Chinese-developed science payloads... Studying gamma-ray bursts, thought to be caused by the death of massive stars or collisions between stars, could provide answers to key questions in astrophysics. This includes the death of stars and the creation of black holes.

However the launch of SVOM also created an explosion of its own closer to home.A video posted on Chinese social media site Sina Weibo appears to show a rocket booster falling on a populated area with people running for cover. The booster fell to Earth near Guiding County, Qiandongnan Prefecture in Guizhou province, according to another post...

A number of comments on the video noted the danger posed by the hypergolic propellant from the Long March rocket... The Long March 2C uses a toxic, hypergolic mix of nitrogen tetroxide and unsymmetrical dimethylhydrazine (UDMH). Reddish-brown gas or smoke from the booster could be indicative of nitrogen tetroxide, while a yellowish gas could be caused by hydrazine fuel mixing with air. Contact with either remaining fuel or oxidizer from the rocket stage could be very harmful to individuals.
"Falling rocket debris is a common issue with China's launches from its three inland launch sites..." the article points out.

"Authorities are understood to issue warnings and evacuation notices for areas calculated to be at risk from launch debris, reducing the risk of injuries.

An anonymous reader shared this report from CNBC: Gilead's experimental twice-yearly medicine to prevent HIV was 100% effective in a late-stage trial, the company said Thursday. None of the roughly 2,000 women in the trial who received the lenacapavir shot had contracted HIV by an interim analysis, prompting the independent data monitoring committee to recommend Gilead unblind the Phase 3 trial and offer the treatment to everyone in the study. Other participants had received standard daily pills.
The company expects to share more data by early next year, the article adds, and if its results are positive, the company could bring its drug to the market as soon as late 2025. (By Fridayt the company's stock price had risen nearly 12%.)

There's already other HIV-preventing options, the article points out, but they're taken by "only a little more than one-third of people in the U.S. who could benefit...according to data from the Centers for Disease Control and Prevention." Part of the problem?

"Daily pills dominate the market, but drugmakers are now focusing on developing longer-acting shots... Health policymakers and advocates hope longer-acting options could reach people who can't or don't want to take a daily pill and better prevent the spread of a virus that caused about 1 million new infections globally in 2022."

Where is dark matter, the invisible masses which must exist to bind galaxies together? Stephen Hawking postulated they could be hiding in "primordial" black holes formed during the big bang, writes CNN.

"Now, a new study by researchers with the Massachusetts Institute of Technology has brought the theory back into the spotlight, revealing what these primordial black holes were made of and potentially discovering an entirely new type of exotic black hole in the process." Other recent studies have confirmed the validity of Hawking's hypothesis, but the work of [MIT graduate student Elba] Alonso-Monsalve and [study co-author David] Kaiser, a professor of physics and the Germeshausen Professor of the History of Science at MIT, goes one step further and looks into exactly what happened when primordial black holes first formed. The study, published June 6 in the journal Physical Review Letters, reveals that these black holes must have appeared in the first quintillionth of a second of the big bang: "That is really early, and a lot earlier than the moment when protons and neutrons, the particles everything is made of, were formed," Alonso-Monsalve said... "You cannot find quarks and gluons alone and free in the universe now, because it is too cold," Alonso-Monsalve added. "But early in the big bang, when it was very hot, they could be found alone and free. So the primordial black holes formed by absorbing free quarks and gluons."

Such a formation would make them fundamentally different from the astrophysical black holes that scientists normally observe in the universe, which are the result of collapsing stars. Also, a primordial black hole would be much smaller — only the mass of an asteroid, on average, condensed into the volume of a single atom. But if a sufficient number of these primordial black holes did not evaporate in the early big bang and survived to this day, they could account for all or most dark matter.

During the making of the primordial black holes, another type of previously unseen black hole must have formed as a kind of byproduct, according to the study. These would have been even smaller — just the mass of a rhino, condensed into less than the volume of a single proton... "It's inevitable that these even smaller black holes would have also formed, as a byproduct (of primordial black holes' formation)," Alonso-Monsalve said, "but they would not be around today anymore, as they would have evaporated already." However, if they were still around just ten millionths of a second into the big bang, when protons and neutrons formed, they could have left observable signatures by altering the balance between the two particle types.
Professer Kaiser told CNN the next generation of gravitational detectors "could catch a glimpse of the small-mass black holes — an exotic state of matter that was an unexpected byproduct of the more mundane black holes that could explain dark matter today."

Nico Cappelluti, an assistant professor in the physics department of the University of Miami (who was not involved with the study) confirmed to CNN that "This work is an interesting, viable option for explaining the elusive dark matter."

Jonathan O'Callaghan reports via Scientific American: Despite more than a century of efforts to show otherwise, it seems Albert Einstein can still do no wrong. Or at least that's the case for his special theory of relativity, which predicts that time ticks slower for objects moving at extremely high speeds. Called time dilation, this effect grows in intensity the closer to the speed of light that something travels, but it is strangely subjective: a passenger on an accelerating starship would experience time passing normally, but external observers would see the starship moving ever slower as its speed approached that of light. As counterintuitive as this effect may be, it has been checked and confirmed in the motions of everything from Earth-orbiting satellites far-distant galaxies. Now a group of scientists have taken such tests one step further by observing more than 1,500 supernovae across the universe to reveal time dilation's effects on a staggering cosmic scale. The researchers' findings, once again, reach an all-too-familiar conclusion. "Einstein is right one more time," says Geraint Lewis of the University of Sydney, a co-author of the study.

In the paper, posted earlier this month on the preprint server arXiv.org, Ryan White of the University of Queensland in Australia and his colleagues used data from the Dark Energy Survey (DES) to investigate time dilation. For the past decade, researchers involved with DES had used the Victor M. Blanco Telescope at the Cerro Tololo Inter-American Observatory in Chile to study particular exploding stars called Type 1a supernovae across billions of years of cosmic history. [...] Type 1a supernovae are keystone cosmic explosions caused when a white dwarf -- the slowly cooling corpse of a midsized star -- siphons so much material from a companion that it ignites a thermonuclear reaction and explodes. This explosion occurs once the growing white dwarf reaches about 1.44 times the mass of our sun, a threshold known as the Chandrasekhar limit. This physical baseline imbues all Type 1a supernovae with a fairly consistent brightness, making them useful cosmic beacons for gauging intergalactic distances. "They should all be essentially the same kind of event no matter where you look in the universe," White says. "They all come from exploding white dwarf stars, which happens at almost exactly the same mass no matter where they are."

The steadfastness of these supernovae across the entire observable universe is what makes them potent probes of time dilation -- nothing else, in principle, should so radically and precisely slow their apparent progression in lockstep with ever-greater distances. Using the dataset of 1,504 supernovae from DES, White's paper shows with astonishing accuracy that this correlation holds true out to a redshift of 1.2, a time when the universe was about five billion years old. "This is the most precise measurement" of cosmological time dilation yet, White says, up to seven times more precise than previous measurements of cosmological time dilation that used fewer supernovae. [...] This particular supernova-focused facet of the Dark Energy Survey has concluded, so until a new dataset is taken, White's measurement of cosmological time dilation is unlikely to be beaten. "It's a pretty definitive measurement," says [Tamara Davis of the University of Queensland, a co-author of the paper]. "You don't really need to do any better." Jonathan O'Callaghan is an award-winning freelance journalist covering astronomy, astrophysics, commercial spaceflight and space exploration.

Change Healthcare has confirmed a February ransomware attack on its systems, which brought widespread disruption to the U.S. healthcare system for weeks and resulted in the theft of medical records affecting a "substantial proportion of people in America." TechCrunch: In a statement Thursday, Change Healthcare said it has begun the process of notifying affected individuals whose information was stolen during the cyberattack. The health tech giant, owned by U.S. insurance conglomerate UnitedHealth Group, processes patient insurance and billing for thousands of hospitals, pharmacies and medical practices across the U.S. healthcare sector. As such, the company has access to massive amounts of health information on about a third of all Americans.

The Ontario Science Center, a world-class science and cultural institution in Toronto, is shutting down immediately due to the risk that the building's roof could collapse, the province announced Friday. CBC News: The abrupt closure, which the province says could last years, comes after the government's controversial announcement in 2023 that the popular landmark and attraction would be moved to the Ontario Place site -- a move it says will save costs. "The actions taken today will protect the health and safety of visitors and staff," said Infrastructure Minister Kinga Surma in a news release. "We are making every effort to avoid disruption to the public and help the Ontario Science Centre continue delivering on its mandate."

An engineering report this week by Rimkus Consulting Group showed each of the centre's three buildings contain roof panels in a "distressed, high-risk" condition, the Ministry of Infrastructure said in a news release. The panels require fixing by Oct. 31, 2024 to "avoid further stress due to potential snow load which could lead to roof panel failure," the release said. Fixing the roof will cost between $22 million and $40 million, the ministry said, requiring the centre be closed for up to two years. "These estimates are incomplete and subject to change," said the ministry, noting the costs make up only a "small portion" of the funding needed to keep the science centre open. The government says the centre needs $478 million to tackle its "failing infrastructure" and sustain programming.

A Florida homeowner has filed an unprecedented claim against NASA for damages caused by space debris that crashed through his roof in March. Alejandro Otero is seeking over $80,000 for property damage and other costs after a 1.6-pound metal object from the International Space Station struck his Naples home. NASA confirmed the debris was part of a battery pack jettisoned in 2021. Legal experts, cited by ArsTechnica in the linked story, say the agency's response could set a precedent for future cases involving space debris damage.

"It turns out that mathematicians actually can't agree on the definition of what makes two things equal, and that could cause some headaches for computer programs that are increasingly being used to check mathematical proofs," writes Clare Watson via ScienceAlert. The issue has prompted British mathematician Kevin Buzzard to re-examine the concept of equality to "challenge various reasonable-sounding slogans about equality." The research has been posted on arXiv. From the report: In familiar usage, the equals sign sets up equations that describe different mathematical objects that represent the same value or meaning, something which can be proven with a few switcharoos and logical transformations from side to side. For example, the integer 2 can describe a pair of objects, as can 1 + 1. But a second definition of equality has been used amongst mathematicians since the late 19th century, when set theory emerged. Set theory has evolved and with it, mathematicians' definition of equality has expanded too. A set like {1, 2, 3} can be considered 'equal' to a set like {a, b, c} because of an implicit understanding called canonical isomorphism, which compares similarities between the structures of groups.

"These sets match up with each other in a completely natural way and mathematicians realised it would be really convenient if we just call those equal as well," Buzzard told New Scientist's Alex Wilkins. However, taking canonical isomorphism to mean equality is now causing "some real trouble," Buzzard writes, for mathematicians trying to formalize proofs -- including decades-old foundational concepts -- using computers. "None of the [computer] systems that exist so far capture the way that mathematicians such as Grothendieck use the equal symbol," Buzzard told Wilkins, referring to Alexander Grothendieck, a leading mathematician of the 20th century who relied on set theory to describe equality.

Some mathematicians think they should just redefine mathematical concepts to formally equate canonical isomorphism with equality. Buzzard disagrees. He thinks the incongruence between mathematicians and machines should prompt math minds to rethink what exactly they mean by mathematical concepts as foundational as equality so computers can understand them. "When one is forced to write down what one actually means and cannot hide behind such ill-defined words," Buzzard writes. "One sometimes finds that one has to do extra work, or even rethink how certain ideas should be presented."

An anonymous reader quotes a report from the BBC: A vote against using MDMA as part of therapy for PTSD has provoked a powerful backlash among researchers who study psychedelic drugs. Some 13 million Americans struggle with post-traumatic stress disorder (PTSD). Existing therapies only bring relief for a fraction of patients, and new treatments are sorely needed, according to psychiatrists wrestling with the scale of the problem. So, there was distinct disappointment when an advisory committee at the US Food and Drug Administration (FDA) voted earlier this month against a therapy that many had hoped could offer the first new treatment for PTSD in 25 years. A number of experts who study psychedelics have since spoken out in support of MDMA-assisted therapy for PTSD and have sharply criticized the recommendations of the FDA's Psychopharmacological Drugs Advisory Committee. But some are still optimistic that the treatment might be approved when the FDA delivers its final decision in August.

While MDMA, also commonly known as ecstasy or molly, is listed as a Schedule 1 controlled substance in the US and so is illegal to use outside research, there has been a growing number of studies suggesting that when used with psychotherapy it could have potential for treating PTSD and some other mental health conditions. Ahead of the meeting, FDA approval of MDMA-assisted therapy for PTSD seemed likely, says Sandeep Nayak, an assistant professor of psychiatry at Johns Hopkins University, who investigates psychedelics as treatments for substance use and mood disorders. About two-thirds of people who received three sessions of MDMA and talk therapy no longer qualified for a PTSD diagnosis at the end of two Phase 3 clinical trials. It's an outcome that is "almost double that of existing medications", says Gul Dolen, a neuroscientist at the University of California, Berkeley, who researches the mechanisms of how psychedelics achieve therapeutic effects. "What's more, [the treatment] led to durable improvements in these patients lasting at least six months."

About half of people who enroll in current gold standard PTSD treatments drop out, which is "absurd," says Loree Sutton, a psychiatrist and retired Brigadier General in the US Army. She says new treatments are essential. "We have to do better." "Even if there are risks, we've got to figure this out, because we cannot not let this treatment be available," adds Rachel Yehuda, a professor of psychiatry and neuroscience at the Icahn School of Medicine at Mount Sinai who has conducted studies on the effects of MDMA-assisted therapy for PTSD. "Without it, we're just leaving too many people in suffering that they don't need to be in, and that is not right." The FDA is currently considering an application from California-based drug company Lykos Therapeutics for using MDMA capsules taken in conjunction with therapy in the treatment of PTSD. In the recent FDA advisory meeting, committee members cited apparent flaws in study design and data collection. The nine-hour hearing concluded with committee members voting 9-2 that the available data do not show "that the drug is effective" for PTSD, and voting 10-1 that the benefits of MDMA do not outweigh the risks.

An anonymous reader writes: Scientists have found microplastics in human penises for the first time, as concerns over the tiny particles' proliferation and potential health effects mount. Seven different kinds of microplastics were found in four out of five samples of penis tissue taken from five different men as part of a study published in IJIR: Your Sexual Medicine Journal on Wednesday. Microplastics are polymer fragments that can range from less than 0.2 inch (5 millimeters) down to 1/25,000th of an inch (1 micrometer). Anything smaller is a nanoplastic that must be measured in billionths of a meter. They form when larger plastics break down, either by chemically degrading or physically wearing down into smaller pieces.

Some minuscule particles can invade individual cells and tissues in major organs, experts say, and evidence is mounting that they are increasingly present in our bodies. Study lead author Ranjith Ramasamy, an expert in reproductive urology who conducted the research while working at the University of Miami, told CNN that he used a previous study that found evidence of microplastics in the human heart as a basis for his research. Ramasamy said he wasn't surprised to find microplastics in the penis, as it is a "very vascular organ," like the heart.

Astronomers are observing the sudden awakening of a giant black hole in the constellation of Virgo. "Decades of observations found nothing remarkable about the distant galaxy in the constellation of Virgo, but that changed at the end of 2019 when astronomers noticed a dramatic surge in its luminosity that persists to this day," reports The Guardian. "Researchers now believe they are witnessing changes that have never been seen before, with the black hole at the galaxy's core putting on an extreme cosmic light show as vast amounts of material fall into it." From the report: The galaxy, which goes by the snappy codename SDSS1335+0728 and lies 300m light years away, was flagged to astronomers in December 2019 when an observatory in California called the Zwicky Transient Facility recorded a sudden rise in its brightness. The alert prompted a flurry of new observations and checks of archived measurements from ground- and space-based telescopes to understand more about the galaxy and its past behavior.

The scientists discovered the galaxy had recently doubled in brightness in mid-infrared wavelengths, become four times brighter in the ultraviolet, and at least 10 times brighter in the X-ray range. What triggered the sudden brightening is unclear, but writing in Astronomy and Astrophysics, the researchers say the most likely explanation is the creation of an "active galactic nucleus" where a vast black hole at the centre of a galaxy starts actively consuming the material around it.

Active galactic nuclei emit a broad spectrum of light as gas around the black hole heats up and glows, and surrounding dust particles absorb some wavelengths and re-radiate others. But it is not the only possibility. The team has not ruled out an exotic form of "tidal disruption event," a highly restrained phrase to describe a star that is ripped apart after straying too close to a black hole. Tidal disruption events tend to be brief affairs, brightening a galaxy for no more than a few hundred days, but more measurements are needed to rule out the process.

Researchers have devised a way to extract energy from the photosynthesis process of algae, according to an announcement from Concordia University.

Suspended in a specialized solution, the algae forms part of a "micro photosynthetic power cell" that can actually generate enough energy to power low-power devices like Internet of Things (IoT) sensors. "Photosynthesis produces oxygen and electrons. Our model traps the electrons, which allows us to generate electricity," [says Kirankumar Kuruvinashetti, PhD 20, now a Mitacs postdoctoral associate at the University of Calgary.] "So more than being a zero-emission technology, it's a negative carbon emission technology: it absorbs carbon dioxide from the atmosphere and gives you a current. Its only byproduct is water."

[...] Muthukumaran Packirisamy, professor in the Department of Mechanical, Industrial and Aerospace Engineering and the paper's corresponding author, admits the system is not yet able to compete in power generation with others like photovoltaic cells. The maximum possible terminal voltage of a single micro photosynthetic power cell is only 1.0V. But he believes that, with enough research and development, including artificial intelligence-assisted integration technologies, this technology has the potential to be a viable, affordable and clean power source in the future.

It also offers significant manufacturing advantages over other systems, he says. "Our system does not use any of the hazardous gases or microfibres needed for the silicon fabrication technology that photovoltaic cells rely on. Furthermore, disposing of silicon computer chips is not easy. We use biocompatible polymers, so the whole system is easily decomposable and very cheap to manufacture."
In the paper the researchers also described it as a âoemicrobial fuel cellâ...

"At the height of the COVID-19 pandemic, the U.S. military launched a secret campaign to counter what it perceived as China's growing influence in the Philippines..." reports Reuters.

"It aimed to sow doubt about the safety and efficacy of vaccines and other life-saving aid that was being supplied by China, a Reuters investigation found."

Reuters interviewed "more than two dozen current and former U.S officials, military contractors, social media analysts and academic researchers," and also reviewed posts on social media, technical data and documents about "a set of fake social media accounts used by the U.S. military" — some active for more than five years. Friday they reported the results of their investigation: Through phony internet accounts meant to impersonate Filipinos, the military's propaganda efforts morphed into an anti-vax campaign. Social media posts decried the quality of face masks, test kits and the first vaccine that would become available in the Philippines — China's Sinovac inoculation. Reuters identified at least 300 accounts on X, formerly Twitter, that matched descriptions shared by former U.S. military officials familiar with the Philippines operation. Almost all were created in the summer of 2020 and centered on the slogan #Chinaangvirus — Tagalog for China is the virus.

"COVID came from China and the VACCINE also came from China, don't trust China!" one typical tweet from July 2020 read in Tagalog. The words were next to a photo of a syringe beside a Chinese flag and a soaring chart of infections. Another post read: "From China — PPE, Face Mask, Vaccine: FAKE. But the Coronavirus is real." After Reuters asked X about the accounts, the social media company removed the profiles, determining they were part of a coordinated bot campaign based on activity patterns and internal data.

The U.S. military's anti-vax effort began in the spring of 2020 and expanded beyond Southeast Asia before it was terminated in mid-2021, Reuters determined. Tailoring the propaganda campaign to local audiences across Central Asia and the Middle East, the Pentagon used a combination of fake social media accounts on multiple platforms to spread fear of China's vaccines among Muslims at a time when the virus was killing tens of thousands of people each day. A key part of the strategy: amplify the disputed contention that, because vaccines sometimes contain pork gelatin, China's shots could be considered forbidden under Islamic law...

A senior Defense Department official acknowledged the U.S. military engaged in secret propaganda to disparage China's vaccine in the developing world, but the official declined to provide details. A Pentagon spokeswoman... also noted that China had started a "disinformation campaign to falsely blame the United States for the spread of COVID-19."
A senior U.S. military officer directly involved in the campaign told Reuters that "We didn't do a good job sharing vaccines with partners. So what was left to us was to throw shade on China's."

At least six senior State Department officials for the region objected, according to the article. But in 2019 U.S. Defense Secretary Mark Esper signed "a secret order" that "elevated the Pentagon's competition with China and Russia to the priority of active combat, enabling commanders to sidestep the StateDepartment when conducting psyops against those adversaries."

[A senior defense official] said the Pentagon has rescinded parts of Esper's 2019 order that allowed military commanders to bypass the approval of U.S. ambassadors when waging psychological operations. The rules now mandate that military commanders work closely with U.S. diplomats in the country where they seek to have an impact. The policy also restricts psychological operations aimed at "broad population messaging," such as those used to promote vaccine hesitancy during COVID...

Nevertheless, the Pentagon's clandestine propaganda efforts are set to continue. In an unclassified strategy document last year, top Pentagon generals wrote that the U.S. military could undermine adversaries such as China and Russia using "disinformation spread across social media, false narratives disguised as news, and similar subversive activities [to] weaken societal trust by undermining the foundations of government."

And in February, the contractor that worked on the anti-vax campaign — General Dynamics IT — won a $493 million contract. Its mission: to continue providing clandestine influence services for the military.

Bloomberg reports: A disease caused by a rare "flesh-eating bacteria" that can kill people within 48 hours is spreading in Japan after the country relaxed Covid-era restrictions. Cases of streptococcal toxic shock syndrome (STSS) reached 977 this year by June 2, higher than the record 941 cases reported for all of last year, according to the National Institute of Infectious Diseases, which has been tracking incidences of the disease since 1999.

Group A Streptococcus (GAS) typically causes swelling and sore throat in children known as "strep throat," but some types of the bacteria can lead to symptoms developing rapidly, including limb pain and swelling, fever, low blood pressure, that can be followed by necrosis, breathing problems, organ failure and death. People over 50 are more prone to the disease. "Most of the deaths happen within 48 hours," said Ken Kikuchi, a professor in infectious diseases at Tokyo Women's Medical University. "As soon as a patient notices swelling in foot in the morning, it can expand to the knee by noon, and they can die within 48 hours...."

At the current rate of infections, the number of cases in Japan could reach 2,500 this year, with a "terrifying" mortality rate of 30%, Kikuchi said.