ISS

Russia Left Without Access to ISS Following Structure Collapse During Thursday's Launch (nasaspaceflight.com) 77

After a successful November 27th launch to the International Space Station, Russia discovered an accident had occurred on their launch site's mobile maintenance cabin — when a drone spotted it lying upside down in a flame trench. "The main issue with the structure collapse is that it puts Site 31/6 — the only Russian launch site capable of launching crew and cargo to the International Space Station (ISS) — out of service until the structure is fixed," reports the space-news site NASA Spaceflight There are other Soyuz 2 rocket launch pads, but they are either located at an unsuitable latitude, like Plesetsk, or not certified for crewed flights, like Vostochny, or decommissioned and transferred to a museum, like Gagarin's Start at Baikonur. As a result, Russia is temporarily unable to launch Soyuz crewed spacecraft and Progress cargo ships to the ISS, whose nearest launch (Progress MS-33) was scheduled for December 21....

When the rocket launched, a pressure difference was created between the space under the rocket, where gases from running engines are discharged, and the nook where the [144-ton] maintenance cabin was located. The resulting pressure difference pulled the service cabin out of the nook and threw it into the flame trench, where it fell upside down from a height of 20 m. Photos of the accident showed significant damage to the maintenance cabin, which, according to experts, is too extensive to allow for repairs. The only way to resume launches from Site 31/6 is to install a spare maintenance cabin or construct a new one.

Despite the fact that the fallen structure was manufactured in the 1960s, two similar service cabins were manufactured recently at the Tyazhmash heavy-engineering plant in Syzran for other Soyuz launch complexes at the Guiana Space Center and Vostochny Cosmodrome. The production of each cabin took around two years to complete, however, it was not for an emergency situation.

"Various experts gave different possible estimates of the recovery time of the Site 31 launch complex: from several months to three years."
AI

Can AI Transform Space Propulsion? (fastcompany.com) 43

An anonymous reader shared this report from The Conversation: To make interplanetary travel faster, safer, and more efficient, scientists need breakthroughs in propulsion technology. Artificial intelligence is one type of technology that has begun to provide some of these necessary breakthroughs. We're a team of engineers and graduate students who are studying how AI in general, and a subset of AI called machine learning in particular, can transform spacecraft propulsion. From optimizing nuclear thermal engines to managing complex plasma confinement in fusion systems, AI is reshaping propulsion design and operations. It is quickly becoming an indispensable partner in humankind's journey to the stars...

Early nuclear thermal propulsion designs from the 1960s, such as those in NASA's NERVA program, used solid uranium fuel molded into prism-shaped blocks. Since then, engineers have explored alternative configurations — from beds of ceramic pebbles to grooved rings with intricate channels... [T]he more efficiently a reactor can transfer heat from the fuel to the hydrogen, the more thrust it generates. This area is where reinforcement learning has proved to be essential. Optimizing the geometry and heat flow between fuel and propellant is a complex problem, involving countless variables — from the material properties to the amount of hydrogen that flows across the reactor at any given moment. Reinforcement learning can analyze these design variations and identify configurations that maximize heat transfer.

Science

Scientists Discover People Act More Altruistic When Batman Is Present (futurism.com) 63

Psychology Today reports: In a study conducted in Milan, Italy, and published in November 2025, the sight of a person dressed as Batman led to a nearly doubled rate of people giving up their seat to a pregnant woman. Over the course of 138 subway rides, researchers found that people who saw "Batman" standing near the pregnant woman were far more altruistic than those who did not.

Researchers are calling this the "Batman effect," suggesting a form of "involuntary" mindfulness may be at play. Noticing these subtle social cues appears to shift people's typical, automatic reactions. Most interestingly, 44 percent of the people questioned reported they did not even consciously register Batman's presence... The superhero costume serves as a visual nudge, pulling us out of our default, self-focused mode and into a more generous, attentive state.

More from Futurism: Batman showing up is just one — albeit striking — way of promoting what's called "prosocial behavior," or the act of helping others around you, via introducing an unexpected event, the researchers write. "Our findings are similar to those of previous research linking present-moment awareness (mindfulness) to greater prosociality," said study lead author Francesco Pagnini, a professor of clinical psychology at the Università Cattolica in Milan, in a statement about the work. "This may create a context in which individuals become more attuned to social cues."
Thanks to Black Parrot (Slashdot reader #19,622) for sharing the article.
Earth

Scientists Think They've Solved Why One of History's Most Advanced Civilizations Vanished 89

A new study published in Communications Earth & Environment has reconstructed the climate conditions of the ancient Indus River Valley civilization between 3000 and 1000 B.C., finding that four intense droughts -- each lasting more than 85 years -- likely drove the gradual decline of one of the world's earliest advanced societies.

The research team, led by Hiren Solanki at the Indian Institute of Technology, Gandhinagar, combined paleoclimate data from cave formations and lake records with computer models to determine that the region shifted from wetter-than-present monsoon conditions to prolonged dry spells as the tropical Pacific Ocean warmed. The third drought, peaking around 1733 B.C., proved the most severe: it lasted 164 years, reduced annual rainfall by 13%, and affected nearly the entire region.

Overall temperatures rose by 0.5 degrees Celsius and rainfall dropped between 10 and 20%. These changes shrank lakes and rivers, dried soils, and made agriculture increasingly difficult in areas away from major waterways. Harappan settlements progressively relocated eastward toward the Indus River over roughly 2,000 years. The civilization's long survival under repeated climate stress -- through crop switching, trade diversification, and settlement relocation -- offers lessons for modern communities facing environmental pressures, the researchers said.
Science

Face Transplants Promised Hope. Patients Were Put Through the Unthinkable (theguardian.com) 18

Twenty years after surgeons in France performed the world's first face transplant, the experimental field that procedure launched is now confronting a troubling record of patient deaths, buried negative data and a healthcare system that leaves recipients financially devastated and medically vulnerable.

About 50 face transplants have been performed globally since Isabelle Dinoire received her partial face graft at University Hospital CHU Amiens-Picardie in November 2005. A 2024 JAMA Surgery study reported five-year graft survival of 85% and 10-year survival of 74%, concluding that the procedure is "an effective reconstructive option for patients with severe facial defects." The study did not track psychological wellbeing, financial outcomes, employment status or quality of life. Roughly 20% of face transplant patients have died from rejection, kidney failure, or heart failure.

The anti-rejection medications that keep transplanted faces alive can destroy kidneys and weaken immune systems to the point where routine infections become life-threatening. In the United States, the Department of Defense has funded most operations, treating them as a frontier for wounded veterans, because private insurers refuse to cover the costs. Patients who survive the surgery often find themselves unable to afford medications, transportation to follow-up appointments or basic caregiving. The field's long-term grants cover surgical innovation but not the lifelong needs of the people who receive these transplants.
NASA

NASA Reduces Flights on Boeing's Starliner After Botched Astronaut Mission 24

An anonymous reader shares a report: NASA has slashed the number of astronaut missions on Boeing's Starliner contract and said the spacecraft's next mission to the International Space Station will fly without a crew, reducing the scope of a program hobbled by engineering woes and outpaced by SpaceX. The most recent mishap occurred during Starliner's first crewed test flight in 2024, carrying NASA astronauts Butch Wilmore and Suni Williams. Several thrusters on Starliner's propulsion system shut down during its approach to the ISS.
China

China's Giant Underground Neutrino Observatory Releases Its First Results (scientificamerican.com) 21

China's new JUNO neutrino observatory has delivered world-leading measurements after just 59 days, offering the most precise readings yet of two key neutrino oscillation parameters. "The physics result is already world-leading in the areas that it touches," says particle physicist Juan Pedro Ochoa-Ricoux of the University of California, Irvine, who co-leads a team on JUNO. "In particular, we measured two neutrino oscillation parameters, and that measurement is already for both parameters the best in the world." The results were published in two separate preprints on arXiv.org. Scientific American reports: JUNO's spherical detector, which is akin to a 13-story-tall fishbowl, primarily measures so-called electron antineutrinos spewing from the nearby Yangjian and Taishan nuclear plants. When the particles strike a proton inside the detector, a reaction triggers two light flashes that ping photomultiplier tubes and get converted into electrical signals. The new measurements from these neutrino-proton collisions are now considered the most precise for two oscillation parameters, which act as proxies for differences in their mass, according to Ochoa-Ricoux.

"It is the first time we've turned on a scientific instrument like JUNO that we've been working on for over a decade. It's just tremendously exciting," Ochoa-Ricoux says. "And then to see that we're able to already do world-leading measurements with it, even with such a small amount of data, that's also really exciting." Still, the physicists will need years' worth of neutrino detections to answer the mass-ordering conundrum.

Businesses

Chinese Pharma is On the Cusp of Going Global (economist.com) 47

China's pharmaceutical industry has quietly evolved from a hub for generics and clinical trials into something more ambitious -- a genuine competitor in drug discovery that Western giants are now courting to fill gaps left by looming patent expirations worth over $300 billion by 2030. In the first half of 2025, nearly a third of global licensing agreements signed by big pharma involved Chinese firms, Economist reports, four times the share from 2021. Pfizer agreed in May to pay $1.25 billion to 3SBio for an experimental cancer drug, and GlaxoSmithKline followed in June with a deal valued at up to $12 billion with Hengrui. Chinese companies now run about a third of the world's clinical trials, up from 5% a decade ago.
Mars

NASA Rover Makes a Shocking Discovery: Lightning on Mars (nytimes.com) 15

An anonymous reader shares a report: It is shocking but not surprising. Lightning crackles on Mars, scientists reported on Wednesday. What they observed, however, were not jagged, high-voltage bolts like those on Earth, arcing thousands of feet from cloud to ground. Rather, the phenomenon was more like the shock you feel when you scuff your feet on the carpet on a cold winter morning and then touch a metal doorknob.

"This is like mini-lightning on Mars," Baptiste Chide, a scientist at the Research Institute in Astrophysics and Planetary Science in Toulouse, France, said of the centimeter-scale electrical discharges. Dr. Chide and his colleagues reported the findings in a paper published on Wednesday in the journal Nature. The electrical sparks, although not as dramatically violent as on Earth, could play an important role in chemical reactions in the Martian atmosphere.

Space

Study Claims To Provide First Direct Evidence of Dark Matter (theguardian.com) 72

An anonymous reader quotes a report from the Guardian: Nearly a century ago, scientists proposed that a mysterious invisible substance they named dark matter clumped around galaxies and formed a cosmic web across the universe. What dark matter is made from, and whether it is even real, are still open questions, but according to a study, the first direct evidence of the substance may finally have been glimpsed. More work is needed to rule out less exotic explanations, but if true, the discovery would go down as a turning point in the decades-long search for the elusive substance that is said to make up 27% of the cosmos.

"This could be a crucial breakthrough in unraveling the nature of dark matter," said Prof Tomonori Totani, an astrophysicist at the University of Tokyo, who said gamma rays emanating from the centre of the Milky Way appeared to bear the signature of the substance. [...] To search for potential dark matter signals, Totani analysed data from Nasa's Fermi Gamma-ray Space Telescope, which detects the most energetic photons in the electromagnetic spectrum. He spotted a pattern of gamma rays that appeared to match the shape of the dark matter halo that spreads out in a sphere from the heart of the galaxy. The signal "closely matches the properties of gamma-ray radiation predicted to be emitted by dark matter," Totani told the Guardian. Details are published in the Journal of Cosmology and Astroparticle Physics.

If Totani has seen dark matter at work, the observations suggest it is made from elementary particles 500 times more massive than the proton. But far more work is needed to rule out other astrophysical processes and background emissions that could explain the signals. Totani said the "decisive factor" would be detecting gamma rays with the same spectrum from other regions of space, such as dwarf galaxies. According to Prof Justin Read, an astrophysicist at the University of Surrey, the lack of significant signals from such galaxies strongly argues against Totani having seen gamma rays emitted from dark matter particle annihilation.
Prof Kinwah Wu, a theoretical astrophysicist at UCL, urged caution, saying: "I appreciate the author's hard work and dedication, but we need extraordinary evidence for an extraordinary claim," he said. "This analysis has not reached this status yet. It is a piece of work which serves as an encouragement for the workers in the field to keep on pressing."
China

China Launches An Emergency Lifeboat To Bring Three Astronauts Back To Earth (arstechnica.com) 26

China launched an uncrewed Shenzhou 22 spacecraft to serve as an emergency lifeboat for three astronauts aboard the Tiangong space station after a docked return craft was found to have a cracked window likely caused by space debris. "A Long March 2F rocket fired its engines and lifted off with the Shenzhou 22 spacecraft, carrying cargo instead of a crew, at 11:11 pm EST Monday (04:11 UTC Tuesday)," reports Ars Technica. "The spacecraft docked with the Tiangong station nearly 250 miles (400 kilometers) above the Earth about three-and-a-half hours later." From the report: Chinese engineers worked fast to move up the launch of the Shenzhou 22, originally set to fly next year. On November 4, astronauts discovered one of the two crew ferry ships docked to the Tiangong station had a damaged window, likely from an impact with a small fragment of space junk. [...] Now, 20 days after the saga began, the Tiangong outpost again has a lifeboat for its long-term residents. Astronauts Zhang Lu, Fu Wei, and Zhang Hongzhang will return to Earth on the Shenzhou 22 spacecraft next year, soon after the arrival of their three replacements.

The Tiangong astronauts will head outside the station on a spacewalk to inspect the damaged window on Shenzhou 20. Eventually, Shenzhou 20 will depart Tiangong and reenter the atmosphere with cargo. Assuming a smooth landing, Chinese engineers will have an opportunity to get a closer look at the damage on the ground to inform the design of future spacecraft. A preliminary assessment of the window indicates the crack is in the outermost layer of heat-insulating glass in Shenzhou 20's porthole window, according to Chinese state media. Engineers on the ground conducted simulations and wind tunnel ablation tests to determine whether the window might fail during reentry. "The results showed that the cracks would still propagate further," reported CCTV, China's government-run television network. "We held review meeting, and everyone agreed that ensuring the safe return of the astronauts was too risky with the glass damaged," Zhou said.

While this crew is just one month into their planned six-month expedition, an emergency could force them to leave the station and return home at any time. Although remote, another collision with space junk, a major systems failure, or a medical emergency involving one of the astronauts could trigger an evacuation. That's why Chinese officials wanted to quickly launch Shenzhou 22 to give the crew a ticket home.The International Space Station follows the same policy, with SpaceX's Dragon spacecraft and Russian Soyuz ships serving as lifeboats until their crews' scheduled return to Earth.

Science

Adolescence Lasts Into 30s - New Study Shows Four Pivotal Ages For Your Brain (bbc.com) 38

The brain goes through five distinct phases in life, with key turning points at ages nine, 32, 66 and 83, scientists have revealed. From a report: Around 4,000 people up to the age of 90 had scans to reveal the connections between their brain cells. Researchers at the University of Cambridge showed that the brain stays in the adolescent phase until our early thirties when we "peak." They say the results could help us understand why the risk of mental health disorders and dementia varies through life. The brain is constantly changing in response to new knowledge and experience -- but the research shows this is not one smooth pattern from birth to death.

Some people will reach these landmarks earlier or later than others -- but the researchers said it was striking how clearly these ages stood out in the data. These patterns have only now been revealed due to the quantity of brain scans available in the study, which was published in the journal Nature Communications.

Sci-Fi

Mind-Altering 'Brain Weapons' No Longer Only Science Fiction, Say Researchers (theguardian.com) 35

Researchers warn that rapid advances in neuroscience, pharmacology, and AI are bringing "brain weapons" out of science fiction and into real-world plausibility. They argue current arms treaties don't adequately cover these emerging tools and call for a new, proactive framework to prevent the weaponization of the human mind. The Guardian reports: Michael Crowley and Malcolm Dando, of Bradford University, are about to publish a book that they believe should be a wake-up call to the world. [...] The book, published by the Royal Society of Chemistry, explores how advances in neuroscience, pharmacology and artificial intelligence are coming together to create a new threat. "We are entering an era where the brain itself could become a battlefield," said Crowley. "The tools to manipulate the central nervous system -- to sedate, confuse or even coerce -- are becoming more precise, more accessible and more attractive to states."

The book traces the fascinating, if appalling, history of state-sponsored research into central nervous system (CNS)-acting chemicals. [...] The academics argue that the ability exists to create much more "sophisticated and targeted" weapons that would once have been unimaginable. Dando said: "The same knowledge that helps us treat neurological disorders could be used to disrupt cognition, induce compliance, or even in the future turn people into unwitting agents." The threat is "real and growing" but there are gaps in international arms control treaties preventing it from being tackled effectively, they say. [...]

The book makes the case for a new "holistic arms control" framework, rather than relying on existing arms control treaties. It sets out a number of practical steps that could be taken, including establishing a working group on CNS-acting and broader incapacitating agents. Other proposals concern training, monitoring and definitions. "We need to move from reactive to proactive governance," said Dando. Both men acknowledge that we are learning more about the brain and the central nervous system, which is good for humanity. They said they were not trying to stifle scientific progress and it was about preventing malign intent. Crowley said: "This is a wake-up call. We must act now to protect the integrity of science and the sanctity of the human mind."

Medicine

Obesity Jab Drug Fails To Slow Alzheimer's (bbc.com) 20

Drug maker Novo Nordisk says semaglutide, the active ingredient for the weight loss jab Wegovy, does not slow Alzheimer's -- despite initial hopes that it might help against dementia. From a report: Researchers began two large trials involving more than 3,800 people after reports the medicine was having an impact in the real world. But the studies showed the GLP-1 drug, which is already used to manage type 2 diabetes and obesity, made no difference compared to a dummy drug. The disappointing results are due to be presented at an Alzheimer's disease conference next month and are yet to be published in a peer-reviewed journal.
Mars

New Mars Orbiter Manuever Challenges Theory: That May Not Be an Underground Lake on Mars (phys.org) 8

In 2018 researchers claimed evidence of a lake beneath the surface of Mars, detected by the Mars Advanced Radar for Subsurface and Ionosphere Sounding instrument (or Marsis for short).

But new Mars observations "are not consistent with the presence of liquid water in this location and an alternative explanation, such as very smooth basal materials, is needed." Phys.org explains Aboard the Mars Reconnaissance Orbiter, the Shallow Radar (SHARAD) uses higher frequencies than MARSIS. Until recently, though, SHARAD's signals couldn't reach deep enough into Mars to bounce off the base layer of the ice where the potential water lies — meaning its results couldn't be compared with those from MARSIS. However, the Mars Reconnaissance Orbiter team recently tested a new maneuver that rolls the spacecraft on its flight axis by 120 degrees — whereas it previously could roll only up to 28 degrees. The new maneuver, termed a "very large roll," or VLR, can increase SHARAD's signal strength and penetration depth, allowing researchers to examine the base of the ice in the enigmatic high-reflectivity zone. Gareth Morgan and colleagues, for their article published in Geophysical Research Letters, examined 91 SHARAD observations that crossed the high-reflectivity zone.

Only when using the VLR maneuver was a SHARAD basal echo detected at the site. In contrast to the MARSIS detection, the SHARAD detection was very weak, meaning it is unlikely that liquid water is present in the high-reflectivity zone.

Moon

Was the Moon-Forming Protoplanet 'Theia' a Neighbor of Earth? (mps.mpg.de) 21

Theia crashed into earth and formed the moon, the theory goes. But then where did Theia come from? The lead author on a new study says "The most convincing scenario is that most of the building blocks of Earth and Theia originated in the inner Solar System. Earth and Theia are likely to have been neighbors."

Though Theia was completely destroyed in the collision, scientists from the Max Planck Institute for Solar System Research led a team that was able to measure the ratio of tell-tale isotopes in Earth and Moon rocks, Euronews explains: The research team used rocks collected on Earth and samples brought back from the lunar surface by Apollo astronauts to examine their isotopes. These isotopes act like chemical fingerprints. Scientists already knew that Earth and Moon rocks are almost identical in their metal isotope ratios. That similarity, however, has made it hard to learn much about Theia, because it has been difficult to separate material from early Earth and material from the impactor.

The new research attempts a kind of planetary reverse engineering. By examining isotopes of iron, chromium, zirconium and molybdenum, the team modelled hundreds of possible scenarios for the early Earth and Theia, testing which combinations could produce the isotope signatures seen today. Because materials closer to the Sun formed under different temperatures and conditions than those further out, those isotopes exist in slightly different patterns in different regions of the Solar System.

By comparing these patterns, researchers concluded that Theia most likely originated in the inner Solar System, even closer to the Sun than the early Earth.

The team published their findings in the journal Science. Its title? "The Moon-forming impactor Theia originated from the inner Solar System."
Space

Are Astronomers Wrong About Dark Energy? (cnn.com) 30

An anonymous reader shared this report from CNN: The universe's expansion might not be accelerating but slowing down, a new study suggests. If confirmed, the finding would upend decades of established astronomical assumptions and rewrite our understanding of dark energy, the elusive force that counters the inward pull of gravity in our universe...

Last year, a consortium of hundreds of researchers using data from the Dark Energy Spectroscopic Instrument (DESI) in Arizona, developed the largest ever 3D map of the universe. The observations hinted at the fact that dark energy may be weakening over time, indicating that the universe's rate of expansion could eventually slow. Now, a study published November 6 in the journal Monthly Notices of the Royal Astronomical Society provides further evidence that dark energy might not be pushing on the universe with the same strength it used to. The DESI project's findings last year represented "a major, major paradigm change ... and our result, in some sense, agrees well with that," said Young-Wook Lee, a professor of astrophysics at Yonsei University in South Korea and lead researcher for the new study....

To reach their conclusions, the researchers analyzed a sample of 300 galaxies containing Type 1a supernovas and posited that the dimming of distant exploding stars was not only due to their moving farther away from Earth, but also due to the progenitor star's age... [Study coauthor Junhyuk Son, a doctoral candidate of astronomy at Yonsei University, said] "we found that their luminosity actually depends on the age of the stars that produce them — younger progenitors yield slightly dimmer supernovae, while older ones are brighter." Son said the team has a high statistical confidence — 99.99% — about this age-brightness relation, allowing them to use Type 1a supernovas more accurately than before to assess the universe's expansion... Eventually, if the expansion continues to slow down, the universe could begin to contract, ending in what astronomers imagine may be the opposite of the big bang — the big crunch. "That is certainly a possibility," Lee said. "Even two years ago, the Big Crunch was out of the question. But we need more work to see whether it could actually happen."

The new research proposes a radical revision of accepted knowledge, so, understandably, it is being met with skepticism. "This study rests on a flawed premise," Adam Riess, a professor of physics and astronomy at the Johns Hopkins University and one of the recipients of the 2011 Nobel Prize in physics, said in an email. "It suggests supernovae have aged with the Universe, yet observations show the opposite — today's supernovae occur where young stars form. The same idea was proposed years ago and refuted then, and there appears to be nothing new in this version." Lee, however, said Riess' claim is incorrect. "Even in the present-day Universe, Type Ia supernovae are found just as frequently in old, quiescent elliptical galaxies as in young, star-forming ones — which clearly shows that this comment is mistaken. The so-called paper that 'refuted' our earlier result relied on deeply flawed data with enormous uncertainties," he said, adding that the age-brightness correlation has been independently confirmed by two separate teams in the United States and China... "Extraordinary claims require extraordinary evidence," Dragan Huterer, a professor of physics at the University of Michigan in Ann Arbor, said in an email, noting that he does not feel the new research "rises to the threshold to overturn the currently favored model...."

The new Vera C. Rubin Observatory, which started operating this year, is set to help settle the debate with the early 2026 launch of the Legacy Survey of Space and Time, an ultrawide and ultra-high-definition time-lapse record of the universe made by scanning the entire sky every few nights over 10 years to capture a compilation of asteroids and comets, exploding stars, and distant galaxies as they change.

Science

Physicists Reveal a New Quantum State Where Electrons Run Wild (sciencedaily.com) 17

ScienceDaily reports: Electrons can freeze into strange geometric crystals and then melt back into liquid-like motion under the right quantum conditions. Researchers identified how to tune these transitions and even discovered a bizarre "pinball" state where some electrons stay locked in place while others dart around freely. Their simulations help explain how these phases form and how they might be harnessed for advanced quantum technologies...

When electrons settle into these rigid arrangements, the material undergoes a shift in its state of matter and stops conducting electricity. Instead of acting like a metal, it behaves as an insulator. This unusual behavior provides scientists with valuable insight into how electrons interact and has opened the door to advances in quantum computing, high-performance superconductors used in energy and medical imaging, innovative lighting systems, and extremely precise atomic clocks... [Florida State University assistant professor Cyprian Lewandowski said] "Here, it turns out there are other quantum knobs we can play with to manipulate states of matter, which can lead to impressive advances in experimental research."

Biotech

Tiny 'Micro-Robots' in your Bloodstream Could Deliver Drugs with Greater Precision (msn.com) 30

The Washington Post reports: Scientists in Switzerland have created a robot the size of a grain of sand that is controlled by magnets and can deliver drugs to a precise location in the human body, a breakthrough aimed at reducing the severe side effects that stop many medicines from advancing in clinical trials... "I think surgeons are going to look at this," [said Bradley J. Nelson, an author of the paper in Science describing the discovery and a professor of robotics and intelligent systems at ETH Zurich]. I'm sure they're going to have a lot of ideas on how to use" the microrobot. The capsule, which is steered by magnets, might also be useful in treating aneurysms, very aggressive brain cancers, and abnormal connections between arteries and veins known as arteriovenous malformations, Nelson said. The capsules have been tested successfully in pigs, which have similar vasculature to humans, and in silicone models of the blood vessels in humans and animals... Nelson said drug-ferrying microrobots of this kind may be three to five years from being tested in clinical trials. The problem faced by many drugs under development is that they spread throughout the body instead of going only to the area in need... A major cause of side effects in patients is medications traveling to parts of the body that don't need them. The capsules developed in Switzerland, however, can be maneuvered into precise locations by a surgeon using a tool not that different from a PlayStation controller. The navigation system involves six electromagnetic coils positioned around the patient, each about 8 to 10 inches in diameter... The capsules are made of materials that have been found safe for people in other medical tools...

When the capsule reaches its destination in the body, "we can trigger the capsule to dissolve," Nelson said.

Science

CERN Can Now Produce Antihydrogen Atoms Eight Times Faster Than Before (phys.org) 41

fahrbot-bot shares a report from Phys.org: Physicists from Swansea University have played the leading role in a scientific breakthrough at CERN, developing an innovative technique that increases the antihydrogen trapping rate by a factor of ten. The advancement, achieved as part of the international Antihydrogen Laser Physics Apparatus (ALPHA) collaboration, has been published in Nature Communications and could help answer one of the biggest questions in physics: Why is there such a large imbalance between matter and antimatter? According to the Big Bang theory, equal amounts were created at the beginning of the universe, so why is the world around us made almost entirely of matter?

Antihydrogen is the "mirror version" of hydrogen, made from an antiproton and a positron. Trapping and studying it helps scientists explore how antimatter behaves, and whether it follows the same rules as matter. Producing and trapping antihydrogen is an extremely complicated process. Previous methods took 24 hours to trap just 2,000 atoms, limiting the scope of experiments at ALPHA. The Swansea-led team has changed that. Using laser-cooled beryllium ions, the team has demonstrated that it is possible to cool positrons to less than 10 Kelvin (below -263C), significantly colder than the previous threshold of about 15 Kelvin. These cooler positrons dramatically boost the efficiency of antihydrogen production and trapping -- allowing a record 15,000 atoms to be trapped in less than seven hours.

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