Medicine

FDA Approves First New Flu Drug In 20 Years (popsci.com) 39

An anonymous reader quotes a report from Popular Science: The Food & Drug Administration just announced that they had approved the aptly-named Xofluza, the first new antiviral drug in two decades, to help alleviate the symptoms of a flu infection. The reason Xofluza got a priority review from the FDA is that it works through a different mechanism than Tamiflu. Both are antivirals, meaning they prevent the replication of the virus, but they work at different stages in that process. First, a quick primer on how viruses infect you: a virus is basically a packet of genetic material that injects itself into a cell and hijacks the cell's normal replication machinery, forcing it to produce millions of copies of the virus. A protein called viral neuraminidase allows those copies to exit the cell and go infect new parts of your body. Most of our effective antivirals are neuraminidase inhibitors -- the virus can still replicate, but it's prevented from escaping.

Xofluza works by preventing the viral replication in the first place. It blocks viral polymerase, an enzyme that helps make copies of the invading genetic material. This doesn't necessarily make it better or more effective -- the FDA notes that early trials suggest it's about as effective as Tamiflu -- but as the FDA Commissioner Scott Gottlieb pointed out in a press release, "Having more treatment options that work in different ways to attack the virus is important because flu viruses can become resistant to antiviral drugs."

Bitcoin

Chinese Court Rules Bitcoin Should Be Protected As Property (coindesk.com) 51

A Chinese court has ruled that despite the country's central bank's ban on cryptocurrency trading, bitcoin should be legally protected as a property with economic values. CoinDesk reports: The Shenzhen Court of International Arbitration published a case analysis on Thursday via WeChat, detailing its ruling on a recent economic dispute that involved a business contract relating to possession and transfer of crypto assets. According to the case analysis, the unnamed plaintiff signed a contract agreement with the defendant, which allowed the latter to trade and manage a pool of cryptocurrencies on the plaintiff's behalf. However, the plaintiff said the defendant failed and refused to return the cryptocurrencies after an agreed deadline. As a result, they brought the case to the arbitrator, seeking the return of the assets with interest. The court concluded that, whether bitcoin is a legal tender or not, does not have an impact on the fact that bitcoin ownership should be protected legally based on China's contract law, adding: "Bitcoin has the nature of a property, which can be owned and controlled by parties, and is able to provide economic values and benefits."
Google

Google's Smart City Dream Is Turning Into a Privacy Nightmare (engadget.com) 61

schwit1 shares a report from Engadget: Sidewalk Labs, an Alphabet division focused on smart cities, is caught in a battle over information privacy. The team has lost its lead expert and consultant, Ann Cavoukian, over a proposed data trust that would approve and manage the collection of information inside Quayside, a conceptual smart neighborhood in Toronto. Cavoukian, the former information and privacy commissioner for Ontario, disagrees with the current plan because it would give the trust power to approve data collection that isn't anonymized or "de-identified" at the source. "I had a really hard time with that," she told Engadget. "I just couldn't... I couldn't live with that."

Cavoukian isn't the first privacy expert to abandon the Quayside project. Saadia Muzaffar, founder of TechGirls Canada, left the Digital Strategy Advisory Panel earlier this month. In a resignation letter, she said Waterfront Toronto had shown "apathy and [an] utter lack of leadership regarding shaky public trust and social license." The advisory panel was attended "in good faith," she said, but showed "a blatant disregard for resident concerns about data." These disagreements will add to the concerns of Torontonians. Sidewalk Labs still has time to address these issues and create a master plan that will be accepted by everyone. If the company continues to lose public trust, though, there's a good chance residents and government officials will make up their minds and reject the plan before reading the first page.

Security

Trivial Bug In X.Org Server Gives Root Permissions On Linux, BSD Systems (bleepingcomputer.com) 114

An anonymous reader quotes a report from Bleeping Computer: A vulnerability that is trivial to exploit allows privilege escalation to root level on Linux and BSD distributions using X.Org server, the open source implementation of the X Window System that offers the graphical environment. The flaw is now identified as CVE-2018-14665 (credited to security researcher Narendra Shinde). It has been present in xorg-server for two years, since version 1.19.0 and is exploitable by a limited user as long as the X server runs with elevated permissions.

An advisory on Thursday describes the problem as an "incorrect command-line parameter validation" that also allows an attacker to overwrite arbitrary files. Privilege escalation can be accomplished via the -modulepath argument by setting an insecure path to modules loaded by the X.org server. Arbitrary file overwrite is possible through the -logfile argument, because of improper verification when parsing the option. Apart from OpenBSD, other operating systems affected by the bug include Debian and Ubuntu, Fedora and its downstream distro Red Hat Enterprise Linux along with its community-supported counterpart CentOS.

Facebook

Facebook Removes 82 Accounts Linked To Iranian Disinformation Campaign (usatoday.com) 54

Facebook said Friday that it removed 82 pages, groups, and accounts from Iran that tried to sow political discord in the U.S. and U.K. over the course of the last year. USA Today reports: The Facebook announcement, coming two weeks before the midterms, was a bracing reminder of the growing scale and frequency of disinformation operations threatening the United States on social media, some of it tied to foreign governments, even as Facebook adds thousands of new employees and strengthens technology to more quickly root out and take down disinformation campaigns.

The page administrators and account owners typically misrepresented themselves as U.S. citizens, or in a few cases U.K. citizens, to post on politically divisive subjects ripped from the headlines such as the confirmation hearings of Supreme Court Justice Brett Kavanaugh. Last week Twitter disclosed more than 1 million tweets from the same operation.
The Iranian government has no ties to the accounts, but the investigation is still ongoing.
Crime

Tesla Faces FBI Probe Over Model 3 Production Numbers (cnbc.com) 143

A new report from The Wall Street Journal says the FBI is reviewing Tesla's Model 3 production numbers as part of an ongoing criminal probe into whether the company misled investors. "Federal agents are reviewing Tesla's stated Model 3 numbers dating back to early 2017, the Journal reports, citing unnamed sources," CNBC reports. From the report: Tesla had previously said it provided documents to the Department of Justice regarding CEO Elon Musk's controversial take-private tweet -- a blunder that ultimately cost Tesla and Musk a combined $40 million in fraud settlement fees. Now Tesla says it also provided information to the Department of Justice regarding Musk's public statements regarding production numbers of its Model 3 sedan. Tesla says the company has not received "a subpoena, a request for testimony, or any other formal process," but the Journal reported Friday that former Tesla employees have received subpoenas and requests for testimony.
The Internet

California Delays Net Neutrality Law's Enforcement Until After Court Case (arstechnica.com) 76

An anonymous reader quotes a report from Ars Technica: California has agreed to delay enforcement of its net neutrality law until after litigation that will determine whether states can implement their own net neutrality rules. California's net neutrality law was slated to take effect on January 1, 2019. But the Trump administration's Department of Justice and broadband industry sued to block the law and were seeking a preliminary injunction that would halt enforcement until litigation is over.

The DOJ and broadband industry had a good chance of winning a preliminary injunction because the Federal Communications Commission had declared that all state net neutrality rules are preempted. As the DOJ argued, the U.S. District Court for the Eastern District of California must presume that the FCC preemption of state laws is valid since that preemption has not been overturned by any court. In a U.S. District Court filing today, California agreed to take no action to enforce the state net neutrality law until after the U.S. Court of Appeals case is decided and all appeals have been exhausted.

Media

Amazon Has Pulled Ads From Bloomberg Over Controversial 'Big Hack' Chinese Spy Story; Apple Has Not Invited Outlet's Reporters To a Product Event Next Week (buzzfeednews.com) 119

Both Amazon and Apple are taking retributive measures against Bloomberg, which in a report earlier this month alleged that some motherboards used by these companies were hacked by China. From a report: Amazon pulled its fourth quarter advertisements on Bloomberg's website, a move some within the media giant think is retribution for its controversial story alleging that Chinese spies hacked into the online retailer's servers. According to a source in position to know, Amazon's digital media buyer, Initiative, informed Bloomberg's sales staff on October 16 that it would cancel its ad buys for the fourth quarter due to budget cuts. Internally, the source said, the staff received that decision, made only eight days after a previous communication with Initiative confirming that the ads would run, as a direct response to Amazon's displeasure over the October 4 story. (Amazon announced Thursday that its marketing expenses for Q3 2018 were 3.3 billion dollars, up more than 800 million dollars from the year before.) [...] According to multiple sources, Bloomberg was not invited to Apple's fall product event next week in Brooklyn. Further reading: In an Unprecedented Move, Apple CEO Tim Cook Calls For Bloomberg To Retract Its Chinese Spy Chip Story.
United States

Suspicious Packages Spotlight Vast 'Mail Cover' Postal Surveillance System (fastcompany.com) 247

tedlistens writes: As law enforcement investigates possible mail bombs sent to prominent Democratic Party figures and liberal activists, the tools available at their disposal include digital images and delivery metadata commonly associated with mail sent in the United States. The U.S. Postal Service regularly photographs the front and back of every piece of U.S. mail, or about 150 billion parcels, envelopes, and postcards every year. A longstanding practice known as the "mail cover" program enables law enforcement to obtain address information and images of the outsides of mail as part of an investigation without the need for a warrant through the Postal Inspection Service, the U.S. Postal Service's policing arm.

According to a report from CBS News, authorities are currently using "data analytics" to spot similar packages to those identified as containing bombs. Images of packages shared with the press show a common return address, using the misspelled name of Representative and former Democratic National Committee chair Debbie Wasserman Schultz. The Postal Inspection Service doesn't generally comment on its investigative techniques. As part of the mail cover program, mail is routinely digitally photographed as part of the sorting process and even available for recipients to digitally preview in some areas. Apart from threats like bombs, the department says its main focus is on mail theft, fraud, and narcotics cases.

Bitcoin

A Reporter, Posing as Sketchy PR, Asked 28 Media Outlets If They'd Take Money To Publish Content Without Disclosing it Was Advertising. More Than Half Said Yes. (breakermag.com) 63

Corin Faife, writing for BreakerMag: The level of deception used was minimal: we created a fake email account, and claimed to be representing a PR company. There was no fake website or domain associated; it was simply a Gmail address with a profile picture found by image searching "Russian actor." Next we compiled a list of blockchain media sites. This was by no means exhaustive, but to have a sense of the scale of the problem, we needed numbers. All in all, we reached out to 28 sites, and received a yes/no reply from 22 by the time of publication, with two inconclusive. [...] Of the 22 outlets who replied conclusively, 12 of them -- more than half the total -- were willing to publish paid content without disclosing it as such.
Earth

Scientists Push For Government Research Program Focused On Sucking Carbon From Air 222

In a 369-page report, the nation's leading scientific body (consisting of the National Academies of Sciences, Engineering and Medicine) is urging the federal government to begin a research program focused on developing technologies that can remove carbon dioxide from the atmosphere in order to help slow climate change. It is now believed that in order to avoid significant further warming of the planet, big chunks of carbon dioxide in the atmosphere may need to be removed. The New York Times reports: The panel's members conceded that the Trump administration may not find the climate change argument all that compelling, since the president has disavowed the Paris Agreement. But, Dr. Pacala said, it's quite likely that other countries will be interested in carbon removal. The United States could take a leading role in developing technologies that could one day be worth many billions of dollars.

Right now, there are plenty of ideas for carbon removal kicking around. Countries could plant more trees that pull carbon dioxide out of the air and lock it in their wood. Farmers could adopt techniques, such as no-till agriculture, that would keep more carbon trapped in the soil. A few companies are building "direct air capture" plants that use chemical agents to scrub trace amounts of carbon dioxide from the air, allowing them to sell the gas to industrial customers or bury it underground. But, the National Academies panel warned, many of these methods are still unproven or face serious limitations. There's only so much land available to plant new trees. Scientists are still unsure how much carbon can realistically be stored in agricultural soils. And direct air capture plants are still too expensive for mass deployment.
One solution that the National Academies panel recommended was for the United States to set up programs to start testing and deploying carbon removal methods that look ready to go, such as negative emissions biomass plants, new forest management techniques or carbon farming programs.

"At the same time, federal agencies would need to fund research into early-stage carbon removal techniques, to explore whether they may one day be ready for widespread use," reports the NYT.
Medicine

Experts Want To Ban Organophosphate Pesticides To Protect Children's Health (theguardian.com) 71

An anonymous reader quotes a report from The Guardian: Evidence that an entire class of pesticides threatens the health of children and pregnant women is now so arresting that the substances should be banned, an expert panel of toxicologists has said. Exposure to organophosphates (OPs) increases the risk of reduced IQs, memory and attention deficits, and autism for prenatal children, according to the paper, published in Plos Medicine. More than 10,000 tonnes of OP pesticides are sprayed in 24 European countries each year and usage is higher in the US, where the Trump administration is appealing against a federal court ban on chlorpyrifos, one of the most popular agricultural insecticides.

Irva Hertz-Picciotto, the paper's lead author and director of the UC Davis environmental health sciences centre, said: "We have compelling evidence from dozens of human studies that exposures of pregnant women to very low levels of organophosphate pesticides put children and fetuses at risk for developmental problems that may last a lifetime. By law, the EPA cannot ignore such clear findings: It's time for a ban not just on chlorpyrifos, but all organophosphate pesticides."
Bruce Lanphear, one of the paper's co-authors, said: "We found no evidence of a safe level of organophosphate pesticide exposure for children. Well before birth, organophosphate pesticides are disrupting the brain in its earliest stages, putting them on track for difficulties in learning, memory and attention, effects which may not appear until they reach school-age. Government officials around the world need to listen to science, not chemical lobbyists."

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