In a posting to the Guile developers list today, it was announced that the Emacs-Lisp compiler for Guile has matured enough to run actual elisp programs. The author included a screencast demoing the new compiler running the Dunnet dungeon crawler. It is still a bit hackish: you need a load file that fakes a few Emacs side functions. In theory, most batch mode programs that don't do buffer manipulation should now work. After a few previous attempts, things could be on track for GNU Emacs 25 based on Guile.