Bionic Retinas Give Patients Sight 199
The Noof writes "
Yahoo News is running a
story about patients who have been given partial sight thanks to implants
of silicon-based bionic retinas.
" The article notes that the implant is having a "rescue effect" on the other components of the retina, restoring cells around the implant and making them useful again." Amazing stuff.
We have the technology (Score:1, Funny)
Lose the arm.
Was I the only one...? (Score:3, Funny)
Maybe I could use a set of bionic retinas...
Re:Was I the only one...? (Score:2, Insightful)
They only mention that this has been tested on people that have lost their vision - wonder if it'd do anything for people born blind?
I'd like to see more science articles like this on the front page of slashdot!
Re:Was I the only one...? (Score:1)
Re:Was I the only one...? (Score:2, Insightful)
They can re-attach a rat's spinal cord.... why not an optic nerve?
There are a magnitude of congenital vision defects, ranging from retinal damage, internal eye pressure problems, optic nerve problems.. but the strangest to date I have encountered is Congenital Anomaly (the absense of eyes as a result of oxygen treatment as an infant)
Re:Was I the only one...? (Score:3, Interesting)
People who are born with visual impairments that can be corrected with technology (i.e. not visual cortex failure) have very low chances of worthwhile results.
When the brain never receives stimulus in a cortex, it never forms any pathways. That portion of the brain, while functional, makes no connections with anything else. A person with visual implants might be able to see as well (maybe better) than you and I, but they wouldn't understand what they saw. They would have technical function but no visual acuity.
This same issue has been demonstrated in people who grew up deaf. They may obtain the ability to hear, but understanding is something they can most likely never acheive. The new sense has missed the "formative" years of the brain, and the individual will never be able to use the sense as others do.
For those who have a hard time comprehending this concept (which is completely understandable), liken it to suddenly having wings surgically attached. Sure, you may have wings, and it's physically possible to fly, but you've never had wings before. They don't work like arms or legs, and you'll probably never learn to control them well enough to fly.
If you still aren't sure, watch At First Sight [mgm.com]. It shows quite well the problems a person would face were they to regain sight. And keep in mind, he once could see.
Re:Was I the only one...? (Score:2)
question (Score:4, Insightful)
Neat stuff.
Re:question (Score:5, Interesting)
Let's build on that. How dense could the sensors get before the optical limits of the eye would become the bottleneck?
Also, since these things are using the photo-voltaic effect to generate the electrical impulse, isn't there a limit to how well they would work in low light? Can that limit be overcome? Could they build units that grabbed inductive power from a transmitter in your glasses to overcome that problem, or maybe even allow super night vision? Will future soldiers be encouraged to get such implants? On the opposite side of that equation, would they allow you to look at the sun without being damaged?
Re:question (Score:5, Interesting)
A good starter paper might be the classic "What the Frog's Eye Tells The Frog's Brain" by McCullough, Pitts and Lettvin. (From MIT's RLE Lab in the 50's) More recently, Marr's stuff is supposed to be very good.
Re:question (Score:2)
you can see in higher resolution than should be optically possible
That seems very counter-intuitive, but since you've suggested it, I can postulate at least one way that could be achieved: When something moves, you get multiple samples per cell, which the optical-neural system could then be intelligently integrating into a higher resolution picture. If that's true though, it wouldn't help you when staring intently at something that isn't moving.
If those papers can suggest anything that allows you to improve resolution when neither the subject nor the optical receptors are moving, I will be truly impressed. Actually, I think that's impossible but I can't prove it off the top of my head.
Re:question (Score:2)
I should note that research has looked at this. If you look at a single point, you can observe a blackout effect. All but the point you're looking at slowly goes dark until only what you're looking at is identifiable. (Or I'm forgetting, and everything goes darker. Its been a few years since that course in college.) The net result is that most of what you see is triggered by changing light levels, not the static images you look at for a few milliseconds at a time.
Re:question (Score:2)
I bet these people in the trial already have a form of "night vision" from their implant. The human eye's response to light cuts off at ~700nm; most photosensitive electronics extend well past that. All you'd need to do is buy one of these [gadgethome.com] and plug it in!
Re:question (Score:2)
>I bet these people in the trial already have a form of "night vision" from their implant. The human eye's response to light cuts off at ~700nm; most photosensitive electronics extend well past that.
I think it's even better:
Currently, night vision means light amplification or light conversion (from Infrared to visible). These electronics could possibly enable you to SEE those frequencies without converting them to the conventional "visible" spectrumo (430-700nm). Imagine SEEing Infrared and/or UV.... new colours!!!!!!!!
Re:question (Score:2)
As both the retina and lens system both evolved more or less simulatiously this is only to be expected.
The point spread function primary and secondary peaks map onto two photoreceptors.
In the dark the iris is larger, so the psf is larger.
To get better vision would require adaptive optics (like used in telescopes) and we're not even sure if the brain could handle it
Re:question (Score:3, Interesting)
Absolutely seriously. My eyes aren't in that bad of shape, but they aren't exactly perfect either. Plus I can't see IR or UV. If bionic eyes were tested enough to be completely safe and healthy for the body, as well as 99.999% reliable (preferably 100%), they could be considered a reliable replacement. Add in a few features like integration into computing systems, switching between UV detection, IR detection, and traditional visible light detection, etc, and you would have some really awesome eyes. I would absolutely pick up a pair of these if they were cheap enough and fail safe enough. It would almost be a step toward Predator type systems, just get me a shoulder cannon and I'm all set
Re:question (Score:2, Interesting)
Just Kidding
And, for the inner pervert in us, if these things could see IR well enough.. Well, just think about the Sony Handycam. Cheers!
Re:question (Score:1)
Re:question (Score:3, Informative)
Re:question (Score:2)
(Although, FWIW, as soon as these things are approved for use, my wife will be getting them.)
Uh Oh... (Score:1, Funny)
Re:Uh Oh... (Score:1, Funny)
wow, neat stuff (Score:1)
They only mention that this has been tested on people that have lost their vision - wonder if it'd do anything for people born blind?
I'd like to see more science articles like this on the front page of slashdot!
Re:wow, neat stuff (Score:1)
Re:wow, neat stuff (Score:2, Redundant)
Re:wow, neat stuff (Score:1)
Maybe they can give these to referees! (Score:1, Funny)
Thank goodness (Score:1)
Re:Thank goodness (Score:3, Interesting)
Rather, there is no apparent blind community to those who are not directly involved with it.
Having blind family members, I can say that there is actually a very large blind community, which I believe is necessary. It is important to realize that people with certain types of disabilities have different struggles and lifestyles then the general population, and being involved with others who share the same experiences can definately help in making life a little easier and pleasent.
Also from my experience, people who have been blind from birth or early childhood would likely not chose to have an implant/surgery to correct the blindness for a few reasons.
First, those adults who were blind from birth have areas in the brain responsible for sight that are not developed because they have never used them. If one of these people were to undergo a operation to correct the blindness, the person's brain would still not be able to interperet the stimulus in a coherent manner. They would see, but they wouldn't understand what they were seeing.
Second (even if the first was not an issue), could you imagine viewing the world in a certain manner, and then one day, having all your preconceptions about everything shatter?
People who have been blind from birth have never seen(duh!), but they do however have an understanding about seeing (ie. colors, patterns, etc.). This differs from the actual experience of seeing as we know it, and taking those concepts away would be tramatic. Most people would be unable to cope with this.
Lastly, this is part of who the person is no matter how much it is disliked or how much of an inconvience it is. It is accepted, much like other things that (for the most part) cannot be changed. Having a hatred for something that is a piece of one's self, that cannot easily be changed, is unhealthy. So is having false dreams about "miracles" or "cures".
Re:Thank goodness (Score:2)
What he's referring to is likely that there are significant groups in the deaf community that are heavily opposed to "fixing" deafness with implants or similar, and believe it should be left as is, and that to accept implants implies that being deaf isn't "normal". Some deaf groups even consider implants a treat to particular cultural elements of the deaf community.
While I'm sure there are many blind people that would not personally want to use implants like these for whatever reason, the poster you replied to was implying that there is no strong element in the blind community that opposes such implants in principle.
Re:Thank goodness (Score:2)
... I'd certainly be first in line to enhance *my* perceptual capabillities. I'd like to be able to see in infrared, have macro-zoom abillities (preferably stereoscopic), micromillimetre radar and some form of high-rez sonar. Why not?
Oh, and there's prolly other stuff as well, like being able to sense electromagnetic fields(sp?)...
Re:Thank goodness (Score:2)
This differs from the actual experience of seeing as we know it, and taking those concepts away would be tramatic. Most people would be unable to cope with this.
People have their preconceptions shattered every day. You are right, it can be a very traumatic experience, but people can and do cope with it, often so well that they become more than they were previously as a result. I think you are wrong to asert that most people would be unable to cope with it. I'm not even sure most people would choose not to cope with it and remain blind, given the choice.
Lastly, this is part of who the person is no matter how much it is disliked or how much of an inconvience it is.
Being cancer prone, or obese, or having a sexual dysfunction is also a part of what a person is. People change, sometimes for the worse, hopefully for the better.
Althoug I have no idea what it would be like to be blind, I can say with absolute certainty that if someone came along and offered to implant a Guizgovot(tm), that would offer me a new sense hitherto unknown to any life form on earth ("a gestalt sense of mean density of matter within two hundred miles, with acuity down to the molecular level accessible by different levels of concentration and focus, coupled or decoupled from the mean electromagnetic flux of the same" the advertisment might read) I would jump at the opportunity to enhance myself in such a way, even being relatively clueless as to how my mind would interpret such a sense, or what good it would do me. An opportunity to experience the world around me with a new and different sense, to sense it in a whole new way, would be a profoundly precious opportunity.
It might change an aspect of who I am, and certainly become a part of who I am, but it by no means would denigrate my identity or eradicate who I was. Neither would getting a prosthetic eye to replace a dysfunctional one, any more than a wheelchair, or a walker, denigrates the identity of or changes who a person with said disability is.
Deaf people who are objecting to devices that can cure deafness, which is by any reasonable definition a deficit or challenge, if not an outright disability, are simply luddite jackasses IMHO, and while deafness might be a blessing in some situations (a screeching el-train going by comes to mind as one) and sign language is something we all should probably learn anyway (I've often wished I could hold a conversation in sign language when hanging out in a loud bar, or, again, as a loud train goes by overhead), rejecting access to a new sense because you think it somehow denigrates others with the same disability is just plain Stupid.
Re:Thank goodness (Score:2)
We talked about it: not only would the blind 'community' embrace this, they are likely to demand the federal government pay to install them on anybody who would benefit.
Cyborgs (Score:1)
Re:Cyborgs (Score:2, Funny)
Too bad we'd all die from heat exhaustion. Well, unless you want to have a liquid cooled rib cage.
Re:Cyborgs (Score:1, Funny)
Re:Cyborgs (Score:1)
Re:Cyborgs (Score:1)
Another thing that bothers me. I keep making predictions, and I either denounce them myself before saying something or someone says I'm just paraniod (wearing a tin foil cap). Yet I see a bunch of the stuff I guessed happening. I seriously hope this doesn't.
Bah, maybe I'm just paranoid for no good reason.
Improvements (Score:4, Interesting)
How about that "cybog" professor and all the hassles he had getting past airport security. While these things are tiny, I can easily forsee a future whene implants are regulated country-by-country.
"Sorry sir. Memory-storage implants are not legal in Canada. You must reboard the airplane."
Johnny Mnemonic, here we come.
Re:Improvements (Score:3, Funny)
Re:Improvements (Score:2)
Re:Or worse yet... (Score:2)
Solar powered eyes? (Score:2, Interesting)
Could this technology have a function in cameras?
What happens at night? (Score:2)
Still, interesting stuff.
I wonder... (Score:1, Funny)
Re:I wonder... (Score:1)
Can it be DoS'd? (Score:4, Interesting)
What kind of interference will upset the function of this device which wouldn't affect a normal eye? Can it be remotely manipulated in such a way as to malfunction or function in a way that a remote attacker may desire it to function?
The fact that I have to ask these questions makes me hesitant to put electronics in my head, but I can imagine that the concern would be less for someone who couldn't see without them.
Re:Can it be DoS'd? (Score:2, Interesting)
Fortunately the eye works differently than the typical I/O interface. Retinal neurons adjust quickly to stimilation and adjust firing patterns. Just think how quickly your eyes adjust to stepping out into a dark room from the sunlight or vice versa. Any permanent damage to the eye is usually from something physical rather than electrical. You can only burn out your eyes from looking at the sun and it's UV or whatever.
Also there is something called deploarization block in which the cell will simply not fire even if there is strong enough imput.
The other big factor is that while all the signalling is coming from this mechanical interface, all the interpretation is done in the Occipital Lobe and we don't and I don't think ever will have a great enough understanding of the brain to hack it.
Re:Can it be DoS'd? (Score:1)
Yes but perhaps not in the way you think. While something like this has a possibility of being hacked, it will only be if someone puts backdoors into the low level hardware controlling the electrical signals along with the remote controller.
You don't suppose that the different material it is made out of might be somewhat affected by properly patterned RF transmissions? I know that silicon is much more responsive to RF than the usual tissue in that area is, perhaps this could be used to give people UV or IR vision rather than (or in addition to) normal vision. Fascinating stuff either way.
all the interpretation is done in the Occipital Lobe and we don't and I don't think ever will have a great enough understanding of the brain to hack it.
I'm much more of an technological optimist in the sense that I disagree.
Re: prOn (Score:2)
Re:Can it be DoS'd? (Score:2)
That's just great. Really. (Score:4, Insightful)
The INTERNET might help us find a cancer cure. (Score:2)
Forget giving it back... having it is more likely to find us a cure.
Think of all the communication and collaboration that is now possible between researchers around the world. And think of the various distributed computing projects, that use Net-connected PCs to crunch numbers for biomedical research and other causes.
Re:That's just great. Really. (Score:2)
What's more important? Quality of life or quantity?
Quantity of sufficiently good life. I reject both a short but full life and a long but dull life. I want, and will claim for myself, a long (infinite if possible) life full of doing what I want to do. Merely extending life is not the answer; the answer is extending active life, making it so you don't have to "retire" into boredom (even working 'til I drop dead would be better than the purgatory of a mindless retirement home, though I would of course prefer more freedom to work on what I want without needing to worry about money).
imagine having a beowulf cluster of these! (Score:1)
Limited Potential (Score:5, Informative)
A lowdown on retinitis pigmentosa can be found here [demon.co.uk].
Re:Limited Potential (Score:5, Interesting)
Ok calm down... explanation time..
I have had retina reatachment surgery 3 times in two years. this is where they take your eyes out, cut open the 6 rows of stiches in each eye and stick the retina back on. They dont know what is causing it (not bungee jumping or a car accident) and everytime it happens my retina gets a little more cut up and i have all sorts of weird stripes through my vision.
Now you my say.. "tough luck, you have bad eyes, live with it" but you see my whole life is based arround my eyes. I am a visual effects artist for the movies (lately 3d modeling on a movie about a ring) my eyes are my livilyhood.
And so the chance that they are one step closer to being able to replace them matters more to me then anything i have heard all year.
So if this is the "limited potential" you are talking about mr katz then i'm not really sorry for getting excited for nothing
More Info (Score:1)
How it's powered (Score:3, Interesting)
I was wondering how in the world it was powered. Come to find out, it's just a bunch of tiny solar cells according to
this article [howstuffworks.com] at How Stuff Works [howstuffworks.com].
The light coming into the eye is focused on the retina. Solar cells convert light to electricity. Electricity stimulates optic nerves. Voila --Sight!
More technical details (Score:4, Informative)
There's much more detail on the history, design, and development of the device in this EE times article [eetimes.com]. I was especially struck by how they persevered. They started on this in 1990 and things did not go entirely smoothly:
This version of the device contains about 3500 light detecting cells. If this version works out okay, they are planning to develop a much larger version of the chip.
Re:How it's powered (Score:2)
Re:How it's powered (Score:2)
Only for those who lost their sight (Score:4, Informative)
While after the operation he physically had 20/20 vision, he actually saw more along the lines of 20/500. The problem wasn't his eye, but his brain. He just hadn't learned how to fully percieve eyesight. One interesting note is that he does not perceive optical illusions. Since he's well past that critical stage of mental development when one is supposed to get it hardwired, he'll have a rough time getting his eyesight anywhere near normal. In fact, several other people who were blind as small children and had similar operations say they would rather be blind now.
At any rate, while this will certainly be a great help to those who lost their sight as adults... it may not be of too much help to those born blind.
Re:Only for those who lost their sight (Score:3, Insightful)
Children NOW who lose their sight may never BECOME adults who lost their sight as children.
Lose sight at 5, get chip at 6, return to normal life. (Extremly abridged version, minus all the "Learn to see again" stuff.)
This is a wonderful innovation - even if its not for everyone, its a start. And everything has to start somewhere.
Science as a miracle? (Score:2, Interesting)
bionics? (Score:1, Funny)
Re:bionics? (Score:1, Funny)
Re:bionics? (Score:1)
and rush has the bionic ear (Score:1)
let me restate, I have no religious affiliation...
I vote lp
laser surgery.... (Score:1)
--tzan
Re:laser surgery.... (Score:3, Interesting)
Also keep in mind that "seeing something 20 feet away like it's 10 feet away" just means you might see a tiny bit more detail - at 20/20 vision most people can see damn near perfectly out to a LONG distance. Really makes me wonder why someone with 20/20 vision would risk their eyesight just for a marginal improvement.
On this note, anyone remember WHY they chose 20/20 as the standard? Was it arbitrary?
As I just took a final over this... (Score:3, Interesting)
Re:As I just took a final over this... (Score:2)
The neumerator denotes the distance (in feet) the test is given at.
I liked your post and would have probably moderated it up as "+1 Informative" myself, had I moderator points.
However, it's lucky for you the test you vaguely refer to is not on English or Grammar. Your post could be AN A answer. I guess we'll all find out on Friday. (AT WHICH time you will receive your grade, I presume.
Re:laser surgery.... (Score:1)
Isn't It Obvious? (Score:1)
Arbitrary? (Score:2)
20/10 woudl not mean 'a tiny bit more detail'.. it would mean I can read things twice as far away as I can now.
they are already advertising it here (Score:1)
I would be really scared to go under the knife for unnecassary thing though. God might get mad that i am not happy with what he gave me and send me some complications.
Re:laser surgery.... (Score:1)
Re:laser surgery.... (Score:2)
1% may not sound like much, but that's hardly worse than your odds of winning $5 or $10 in one of those McDonalds peel-and-win games on the french-fry boxes....
I would definitely think twice before gambling with my vision like that.
Can you imagine... (Score:1)
(well, someone had to say it)
I wonder how long it'll take until we see NVidia and ATI try to sell us this kind of thing...
RMN
~~~
Re:Can you imagine... (Score:1)
It'll be Zeiss and Nikon. Optics, not graphics.
Ahhh (Score:1)
Stevie Wonder? (Score:2)
Talk about unthankfulness (Score:3, Funny)
"For another patient, though, the implant has been a bit sobering, Chow said. The patient, who has begun to recognize faces, was disappointed to see how his own face had aged."
I can almost hear those doctors now. "Dude. You've been blind for many years, you were chosen to have your sight restored by a groundbreaking scientific process, and the only thing you can think about is how old you are?
Get back on that operating table, I'm gonna yank that damn chip out your eye..."
THIS IS GREAT (Score:1)
If the electric impulses that are interprutted by the brain as sight, touch, etc. can be harnessed think about the newest forms os prosthetic hands android hands that actually work!!! this is fabulous....
I can hardly wait to see more on this subject!!!
Bionic Man (Score:1)
Reporting from ARVO (Score:5, Insightful)
I for one would love to believe in the results, but I have not seen any real scientific proof that these things work as advertised. While the video of patients was impressive and touching, there is very little hard science behind the development of the bionic retina and how it is integrating into the retinal environment. The only thing that everyone appears to be reporting on is that the chip is not rejected. And there are other more fundamental issues at work. For one, the silicon retinas require the equivalent of 3X's the brightness of the sun to activate the device and for realistic performace, they would require an external power source. The other issue is that the retinal circuitry that they are placing this bionic implant onto is severely degenerated and remodeled in these patients and may continue to degenerate further, thus complicating matters. That said, there is some indication that the surgery itself may cause some retinal rescue, not the implant. This is something they have not done control experiments on. Furthermore, the generation of low voltage current from the implant in the retina may be promoting retinal recovery of sorts while the silicon retina may not be doing anything for vision itself.
We are still a looooong ways away from the idea of a bionic retina and I think that retinal implants will actually be the least effective method in the long run. Gene therapy, viral infective methods, stem cells, and post retinal bionics will probably work optimally sooner.
Re:Reporting from ARVO (Score:2)
No, Post retinal bionics are conceptually bionic plug-ins that use the pre-existing retinal ganglion cell axons to wire up to the brain thus bypassing the retina. The axons would probably have to be severed to keep from corrupting the circuits, but the eyeball would remain intact. Removing eyes and then putting them back in does not happen.
Bionic Retina picture (Score:2)
Progress (Score:2)
Sobering Thoughts (Score:3, Insightful)
Sure, it isn't perfect and it's only version
Just step back and realize what an accomplishment this is and how fast technology changes everyday. It's almost scary to think what life will be like when I turn 60.
Reminds me of something my Great Grandfather said: "I've seen the world come from stage coach to walking on the moon; nobody will ever lead that kind of life again."
Well if this is the case I would think the rate of progression will disprove this. It's amazing to think we will all outlive the advancements that occured during his lifetime, but we probably will.
This article just reaffirms that notion.
Once again... real science beats Star Trek (Score:2)
And the MPAA will take them away. (Score:2)
The current MPAA won't like that.
Or if they manage to get it the way they like it, you won't like it.
Link.
Re:figs (Score:1)
Re:Full Article Text (Score:5, Funny)
Re:Full Article Text (Score:2)
Hey, it could be worse, how long to people link to google cache's [216.239.33.100] of the API's [google.com] in Google Releases an API for Their Database [slashdot.org]?
But someone might yet post a link to the google cache of his post, just in case!
Re:Full Article Text (Score:3, Funny)
Re:Full Article Text (Score:1)
What, do you think YAHOO is going to get slashdotted? Get a clue.
Re:Full Article Text (Score:1)
Re:Full Article Text (Score:1)
Yes but could he read